RT Book, Section A1 May, J. Russell A1 Griffin, Dixie D. A1 May, Kathleen A2 Chisholm-Burns, Marie A. A2 Schwinghammer, Terry L. A2 Malone, Patrick M. A2 Kolesar, Jill M. A2 Bookstaver, P. Brandon A2 Lee, Kelly C. SR Print(0) ID 1187023989 T1 Drug Hypersensitivity Reactions T2 Pharmacotherapy Principles & Practice, 6e YR 2022 FD 2022 PB McGraw-Hill Education PP New York, NY SN 9781260460278 LK ppp.mhmedical.com/content.aspx?aid=1187023989 RD 2024/10/06 AB LEARNING OBJECTIVESUpon completion of the chapter, the reader will be able to:Describe the potential incidence of immunoglobulin-E (IgE)- and non-IgE-mediated (immune and nonimmune) drug hypersensitivity reactions and why it is difficult to obtain accurate estimates.Understand the Gell and Coombs categories of immunologic reactions and more recently described immunologic mechanisms.Identify the classes of drugs most commonly associated with IgE- and non–IgE-mediated drug hypersensitivity reactions.Recommend specific treatment for anaphylaxis.Recommend an approach to drug selection in patients with multiple drug sensitivities.Understand the utility of drug challenge and desensitization procedures.