TY - CHAP M1 - Book, Section TI - Lymphomas A1 - Hecht, Keith A. A1 - Liewer, Susanne A2 - Chisholm-Burns, Marie A. A2 - Schwinghammer, Terry L. A2 - Malone, Patrick M. A2 - Kolesar, Jill M. A2 - Bookstaver, P. Brandon A2 - Lee, Kelly C. Y1 - 2022 N1 - T2 - Pharmacotherapy Principles & Practice, 6e AB - LEARNING OBJECTIVESUpon completion of the chapter, the reader will be able to:Discuss the underlying pathophysiologic mechanisms of the lymphomas and how they relate to presenting symptoms of the disease.Differentiate the pathologic findings of Hodgkin lymphoma (HL), follicular indolent non-Hodgkin lymphoma (NHL), and diffuse aggressive NHL and how this information yields a specific diagnosis.Describe the general staging criteria for the lymphomas and how it relates to prognosis; evaluate the role of the prognostic systems such as the International Prognostic Score for HL, the Follicular Lymphoma International Prognostic Index (IPI), and the IPI for diffuse, aggressive NHL.Compare and contrast the treatment algorithms for early and advanced stage disease for HL.Assess the role of autologous hematopoietic stem-cell transplantation for relapsed lymphomas.Delineate the clinical course of follicular indolent and diffuse aggressive NHL and the implications for disease classification schemes and treatment goals.Outline the general treatment approach to follicular indolent and diffuse aggressive NHL for localized and advanced disease.Interpret the current role for monoclonal antibody therapy in NHL. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/09 UR - ppp.mhmedical.com/content.aspx?aid=1187022839 ER -