TY - CHAP M1 - Book, Section TI - Drug Hypersensitivity Reactions A1 - May, J. Russell A1 - Griffin, Dixie D. A1 - May, Kathleen A2 - Chisholm-Burns, Marie A. A2 - Schwinghammer, Terry L. A2 - Malone, Patrick M. A2 - Kolesar, Jill M. A2 - Bookstaver, P. Brandon A2 - Lee, Kelly C. Y1 - 2022 N1 - T2 - Pharmacotherapy Principles & Practice, 6e AB - LEARNING OBJECTIVESUpon completion of the chapter, the reader will be able to:Describe the potential incidence of immunoglobulin-E (IgE)- and non-IgE-mediated (immune and nonimmune) drug hypersensitivity reactions and why it is difficult to obtain accurate estimates.Understand the Gell and Coombs categories of immunologic reactions and more recently described immunologic mechanisms.Identify the classes of drugs most commonly associated with IgE- and non–IgE-mediated drug hypersensitivity reactions.Recommend specific treatment for anaphylaxis.Recommend an approach to drug selection in patients with multiple drug sensitivities.Understand the utility of drug challenge and desensitization procedures. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/05 UR - ppp.mhmedical.com/content.aspx?aid=1187023989 ER -