Chapter 93. Skin Cancer
Which of the following is associated with increased risk of MM?
B. Childhood severe sunburn
Option A: Incorrect. The tendency to sunburn is a risk factor.
Option B: Correct. Childhood sunburns are associated with twice the risk of melanoma.
Option C: Incorrect. The male gender increases risk of MM.
Option D: Incorrect. Vitamin D deficiency is typically associated with reduced sun exposure.
Which of the following is appropriate therapy for recurrent melanoma?
Option A: Incorrect. Ipilimumab is approved as for adjuvant treatment for stage III and unresectable melanoma.
Option B: Incorrect. Melphalan is used in local disease.
Option C: Incorrect. Interferon is not used in metastatic or recurrent disease.
Option D: Correct. Biochemotherapy containing dacarbazine is indicated in metastatic or recurrent disease.
Which of the following patients have the highest risk of developing MM?
A. 40-year-old African American female with dark hair
B. 32-year-old Caucasian male with red hair
C. 55-year-old Caucasian female with dark hair
D. 28-year-old African American male with black hair
Option A: Incorrect. This person possesses no host-related risk factors.
Option B: Correct. The patient has three risk factors: white skin, male gender, and red hair.
Option C: Incorrect. The only risk factor this patient has is white skin.
Option D: Incorrect. The only risk factor this patient has is male gender.
Which of the following is not a rare but serious adverse event of ipilimumab?
Option A: Incorrect. T-cell activation by ipilimumab can lead to enterocolitis.