Skip to Main Content

Chapter 67. Coagulation and Platelet Disorders

Student Questions

Extrinsic coagulation pathway involves:

A. Factor XII

B. Factor VIII

C. Factor VII

D. Factor IX

Answer: C

Option A: Incorrect. F XII is part of intrinsic pathway

Option B: Incorrect. F VIII is part of intrinsic pathway

Option C: Correct. F VII is part of extrinsic pathway

Option D: Incorrect. F IX is part of intrinsic pathway

All of the following processes take part in thrombin formation except:

A. Coagulation

B. Platelet activation

C. Vasoconstriction

D. Fibrinolysis

Answer: D

Option A: Incorrect. Coagulation is one of the processes involved in thrombin formation.

Option B: Incorrect. Platelet activation is one of the processes involved in thrombin formation.

Option C: Incorrect. Vasoconstriction is one of the processes involved in thrombin formation.

Option D: Correct. Fibrinolysis is the process of clot destruction/breakdown.

Which of the following statements is true?

A. Each unit of factor FVIII replacement administered per kilogram of body weight raises the plasma FVIII level 1% (0.01 IU/mL [10 IU/L]).

B. Each unit of FVIII replacement administered per kilogram of body weight raises the plasma FVIII level 2% (0.02 IU/mL [20 IU/L]).

C. Each unit of FIX replacement administered per kilogram of body weight yields a 0.1% rise in plasma (0.001 IU/mL [1 IU/L]) FIX level.

D. Each unit of FIX replacement administered per kilogram of body weight yields a 2% rise in plasma (0.02 IU/mL [20 IU/L]) FIX level.

Answer: B

Option A: Incorrect. Usually FVIII levels increase by 2% (0.02 IU/mL [20 IU/L]) for every 1 unit/kg of FVIII concentrate infused.

Option B: Correct. Usually FVIII levels increase by 2% (0.02 IU/mL [20 IU/L]) for every 1 unit/kg of FVIII concentrate infused.

Option C: Incorrect. Each unit of FIX replacement administered per kilogram of body weight yields a 1% rise in plasma (0.01 IU/mL [10 IU/L]) FIX level.

Option D: Incorrect. Each unit of FIX replacement administered per kilogram of body weight yields a 1% rise in plasma (0.01 IU/mL [10 IU/L]) ...

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.