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Chapter 65. Common Skin Disorders

Student Questions

Which of the following is involved in the development of acne lesions?

A. Normal sebum production

B. Increased androgen levels

C. Hypokeratinization

D. Viral colonization

Answer: B

Option A: Incorrect. Increased sebum production is involved in the development of acne lesions.

Option B: Correct. Increased androgen levels are observed in acne patients.

Option C: Incorrect. Hyperkeratinization results in excess epithelial cell division and adhesiveness which contributes to follicular obstruction.

Option D: Incorrect. Bacterial colonization of Propionibacterium acnes contributes to inflammatory acne. Viral colonization has no role in acne pathogenesis.

Which of the following non-pharmacological recommendations for acne is most appropriate?

A. Squeeze closed comedos to prevent development of inflammatory lesions.

B. Wash face at least three times daily with a non-abrasive cleanser.

C. Moisturize skin daily with an oil-free non-comedogenic moisturizer.

D. Oil-based cosmetics may be used as long as the face is proper cleansed before bedtime.

Answer: C

Option A: Incorrect. Patients should avoid popping or squeezing all types of acne lesions to prevent scarring.

Option B: Incorrect. It is recommended to wash face with non-abrasive cleaner twice per day. Excessive face washing may irritate the skin.

Option C: Correct. Oil-free moisturizers are recommended to improve tolerability of topical acne therapy.

Which of the following therapies is the cornerstone of induction and maintenance treatment in all acne severities because it effectively clears existing lesions, reduces inflammation, and prevents microcomedo formation.

A. Isotretinoin

B. Topical retinoid

C. Dapsone

D. Doxycycline

Answer: B

Option A: Incorrect. Although isotretinoin clears existing lesions and prevents formation of new lesions, it is only recommended for severe acne. Toxicity limits use.

Option B: Correct. Topical retinoids are recommended in all forms of acne as first-line therapy because they are generally well tolerated and effectively clear up existing lesions and prevent formation of new lesions.

Option C: Incorrect. Dapsone therapy is an alternative to other topical agents in patients with mild acne.

Option D: Incorrect. Oral antibiotics are recommended for only induction treatment of moderate ...

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