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Chapter 70. Central Nervous System Infections

A 73-year-old patient with a documented allergy to sulfa agents (bronchoconstriction) should receive which antimicrobial(s) for listeriosis treatment?

A. Ceftriaxone

B. Ampicillin

C. Gentamicin

D. Vancomycin plus gentamicin

Which patient would be assumed to be at the highest risk of meningococcal meningitis?

A. 4-year-old attending daycare

B. 34-year-old pregnant woman

C. 78-year-old hospital volunteer

D. 19-year-old college sophomore

Which of the following antibiotic therapy should be used for pneumococcal meningitis in a patient with a severe, Type 1 allergy to penicillins and cephalosporins?

A. Vancomycin

B. Aztreonam

C. Meropenem

D. Sulfamethoxazole-trimethoprim

Meningococcal vaccine is recommended in which of the following patients:

A. 2-month-old infant

B. 67-year-old woman with diabetes

C. 5-year-old attending daycare

D. 12-year-old attending public school

Which of the following antimicrobial agents should be considered in empirical therapy of postneurosurgical meningitis?

A. Ceftriaxone

B. Cefepime

C. Doxycycline

D. Moxifloxacin

What is the agent of choice for maintenance therapy in cryptococcal meningitis in a patient with a CD4+ count of 33 cells/mm3 (33 × 106/L)?

A. Lipid formulation of amphotericin

B. Posaconazole

C. Micafungin

D. Fluconazole

What is the primary reason for inclusion of vancomycin in empiric treatment of adults with community-acquired bacterial meningitis?

A. Treatment of methicillin-resistant Staphylococcus aureus (MRSA)

B. Treatment of drug-resistant Streptococcus pneumoniae

C. Treatment of drug-resistant Neisseria meningitidis

D. Treatment of methicillin-resistant Staphylococcus epidermidis (MRSE)

Which of the following ...

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