Chapter 44. Thyroid Disorders
The serum T4 level is not a good test for screening and monitoring for thyroid disease because:
A. The assay is difficult to perform and not available in most clinical laboratories
B. The results can be affected by alteration in protein binding, making interpretation difficult
C. It is too sensitive, with a high percent of false positive results
D. Serum T3 is a better test since it is the active hormone
The prevalence of hypothyroidism is higher in:
C. Patients with other autoimmune endocrine disorders
D. Patients treated with amiodarone
E. All of the above are correct
What is the target TSH range (mIU/L or μIU/mL) for patients being treated for hypothyroidism or hyperthyroidism?
Which of the following is a reasonable choice in treating a patient with newly diagnosed hypothyroidism?
E. All are reasonable choices
Levothyroxine products should not be substituted at refill because:
A. No marketed products are AB rated by the FDA Orange Book.
B. All state regulations prohibit the substitution of narrow therapeutic index drugs.
C. Small differences in bioavailability may result in loss of disease control.
D. Patients will be nonadherent if it is switched.
Patients with mild or subclinical hypothyroidism should be considered for LT4 therapy if the patient has:
A. A family history of thyroid disease