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Chapter 37. Schizophrenia

Which of the following statements is not true?

A. If the patient has lack of response to two adequate antipsychotic trials, a trial of clozapine should be considered.

B. All antipsychotics, other than clozapine, have similar efficacy.

C. It is appropriate to choose an antipsychotic based on which side effects will be most tolerable to the patient.

D. All antipsychotics have equal risk of weight gain and metabolic disturbances.

E. The results of the CATIE trial showed some FGAs may be as well tolerated as SGAs.

Which of the following statements regarding the diagnosis of schizophrenia is true?

A. The presence of psychosis is diagnostic for schizophrenia.

B. The presence of disorganization is necessary for diagnosis.

C. Symptoms must be present for at least 1 week.

D. Symptoms must be documented by MRI changes.

E. Social and/or occupational dysfunction must be present.

Which of the following side effects of antipsychotic medications would have a delayed occurrence of onset that is usually months to years after initiation of the medication?

A. Sedation

B. Dry mouth

C. Tardive dyskinesia

D. Weight gain

E. All of the above

Which of the following schizophrenia symptoms is most likely to respond to antipsychotic treatment?

A. Hallucinations

B. Cognition

C. Impaired judgment

D. Disorganization

E. Negative symptoms

Which of the following situations would be the most appropriate for the use of clozapine?

A. A 19-year-old patient first presenting with psychotic symptoms

B. A 65-year-old patient with schizophrenia and multiple myeloma

C. A 43-year-old patient rehospitalized after nonadherence to olanzapine and risperidone.

D. A 35-year-old patient rehospitalized after failing treatment with haloperidol

E. A 33-year-old patient with a lack of response to separate trials of risperidone and aripiprazole


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