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Gastroesophageal Reflux Disease

Chapter 17. Gastroesophageal Reflux Disease

Which one of the following GERD symptom is considered complicated and requires further diagnostic evaluation?

A. Heartburn

B. Regurgitation

C. Chronic cough

D. Difficulty swallowing

E. Hiatal hernia

Extraesophageal syndrome associated with GERD refers to:

A. Erosions of the esophagus

B. Gastroesophageal reflux symptoms associated with disease processes in organs other than the esophagus

C. Inflammation of the esophagus

D. Replacement of the squamous epithelial lining in the esophagus with columnar epithelial lining

E. Barrett esophagus

Which of the following PPI regimens is/are preferred as initial treatment in a 60-year-old patient with erosive esophagitis?

A. Lansoprazole 30 mg once daily × 3 weeks

B. Pantoprazole 40 mg twice daily × 24 weeks

C. Esomeprazole 20 mg once daily × 8 weeks

D. Rabeprazole 20 mg once daily as needed

E. Any of the above would be a preferred treatment

Which of the following PPIs would offer dosing flexibility relative to meal timing?

A. Dexlansoprazole

B. Lansoprazole

C. Omeprazole/sodium bicarbonate

D. Omeprazole

E. A and C only

On-demand therapy would be most appropriate in patients with:

A. Atypical symptoms

B. Intermittent reflux symptoms

C. Barrett esophagus

D. Erosive esophagitis

E. Strictures

Which one of the following medications may worsen the symptoms of GERD by decreasing lower esophageal sphincter pressure?

A. Nifedipine

B. Alendronate

C. Naproxen

D. Quinidine

E. Ferrous sulfate

What is the best ...

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