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Chapter 97. Malignant Lymphomas

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Which of the following kinase inhibitors can be used in the treatment of patients with follicular lymphoma that has progressed despite multiple chemotherapy treatments?

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A. Regorafenib

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B. Vandetanib

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C. Imatinib

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D. Idelalisib

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E. Dasatinib

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Which of the following unique toxicities are associated with the ABVD regimen?

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A. Pulmonary fibrosis

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B. Hemorrhagic cystitis

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C. Hepatic encephalopathy

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D. Osteopenia

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E. All of the above

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For a patient presenting with lymphadenopathy and a suspected diagnosis of lymphoma, the most appropriate diagnostic test would be:

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A. Abdominal x-ray

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B. Fine-needle aspirate

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C. Surgical lymph node excision

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D. Bone scan

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E. Serum protein electrophoresis

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Which of the following prophylactic medications should be administered before the infusion of single-agent rituximab?

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A. Diphenhydramine

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B. Filgrastim

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C. Ondansetron

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D. Allopurinol

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E. Fosaprepitant

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Which of the following agents should not be administered intrathecally for a patient with primary CNS lymphoma?

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A. Cytarabine

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B. Vincristine

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C. Methotrexate

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D. Hydrocorotisone

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E. All of these medications can be administered intrathecally

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Which of the following is not a negative prognostic factor in advanced Hodgkin lymphoma?

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A. Platelets < 100,000/μL (100 × 109/L)

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B. WBCs > 15,000/mm3(15 × 109/L)

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C. Stage IV disease

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D. Male gender

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E. Albumin < 4 g/dL (40 g/L)

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Standard chemotherapy for front-line treatment for advanced (stage III/IV) diffuse large B-cell lymphoma is:

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A. m-BACOD

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B. PROMACE-CytaBOM

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