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Chapter 94. Ovarian Cancer

What family history would suggest that patient needs to be screened for hereditary risk for ovarian cancer?

A. Having a mother and aunt diagnosed with breast cancer

B. Having two cousins diagnosed with ovarian cancer

C. Having a mother with breast cancer and sister with ovarian cancer

D. Having a grandmother and cousin diagnosed with cervical cancer

Which of the following factors may increase risk of developing ovarian cancer?

A. Use of ovulation stimulatory agents

B. Use of phytoestrogen nutritional supplements

C. Short term use of hormone replacement therapy

D. Short-term use of oral contraceptives

A 27-year-old woman presents to your clinic with concerns about her risk of ovarian cancer. She wants to know what will minimize her risk of ovarian cancer. Which of the following would be the best option for a premenopausal woman with no family history of cancer to prevent ovarian cancer?

A. Regular annual pelvic examination

B. Routine transvaginal ultrasonography and CA-125 level

C. Oral contraceptive use

D. Tubal ligation

A46-year-old married premenopausal woman who just completed genetic screening that revealed she is a carrier of the BRCA1 gene. She confirms she has two children and has completed her childbearing years. Which of the following would be the best option to reduce her risk of ovarian cancer?

A. Bilateral salpingo-oophorectomy

B. Mastectomy

C. Hysterectomy

D. Long-term use of oral contraceptive

A28-year-old woman who has mild episodes of diarrhea associated with her irritable bowel syndrome but otherwise is in good health and feels well. She is only child but has no family history of cancer. She just received her results from her gynecologist that she has CA-125 level of 38 kU/L (lab upper limit of normal is 35 kU/L). Based on this information, what follow-up would you recommend to rule out ovarian cancer?

A. Transvaginal ultrasonography.

B. Pelvic examination.

C. Laboratory studies repeated in 6 months.

D. She does ...

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