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Chapter 92. Prostate Cancer

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Which of the following is true regarding finasteride and dutasteride in the prevention of prostate cancer?

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A. Dutasteride is FDA approved for prostate cancer chemoprevention.

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B. Finasteride is FDA approved for prostate cancer chemoprevention.

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C. Both finasteride and dutasteride are FDA approved for prostate cancer chemoprevention.

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D. Neither agent is FDA approved, but the benefits and risks should be discussed with men with a normal PSA result and undergoing regular screening.

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E. Neither agent is FDA approved and should not be used.

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Which of the following does not increase the risk for prostate cancer?

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A. African American ancestry

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B. Older age

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C. Benign prostatic hyperplasia

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D. High-fat diet

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E. Family history

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Which of the following is the gold standard method for diagnosing prostate cancer?

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A. Transrectal ultrasound (TRUS)

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B. Digital rectal examination (DRE)

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C. Prostate tissue biopsy

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D. Prostate-specific antigen (PSA)

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E. Bone marrow biopsy

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Seizures are a rare, but serious adverse effect caused by which of the following medications?

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A. Abiraterone

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B. Enzalutamide

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C. Docetaxel

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D. Sipuleucel-T

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E. Cabazitaxel

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Which of the following is an effective method to decrease the tumor flare syndrome associated with the first few weeks of LHRH agonist therapy?

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A. Start the LHRH agonist with a loading dose to rapidly achieve steady-state levels.

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B. Start an antiandrogen before the LHRH agonist and continue for the first 3 to 4 weeks of therapy.

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C. Start the LHRH agonist with a 50% dose decrease, slowly titrating to a full dose over 3 to 4 weeks.

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D. Alternate LHRH agonists during the first 3 to 4 months of therapy.

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E. Maintain testosterone levels above castration levels.

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A 64-year-old man with newly ...

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