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Chapter 90. Lung Cancer

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All of the following scenarios are consistent with a recommendation to be screened with a low-dose CT scan for lung cancer (according to the recent guidelines)?

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A. A 45-year-old man who has smoked a pack a day since the age of 13 years

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B. A 65-year-old woman with a 40 pack–year smoking history, who quit smoking 10 years ago

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C. A 50-year-old coal miner whose father and brother died of lung cancer in their 60s

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D. All of the above fit the screening criteria

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E. None of the above fit the screening criteria

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Treatment options for a patient with stage IIIb adenocarcinoma and an ECOG PS score of 3 may include all of the following EXCEPT:

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A. Palliative radiotherapy

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B. Surgical resection of a distant metastasis

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C. Platinum-containing doublet chemotherapy

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D. Single agent targeted agent

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E. Treatment of comorbidities to improve performance

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A well-performing stage IV adenocarcinoma NSCLC patient with a mutation in exon 19 of the EGFR gene should be treated with:

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A. Cetuximab

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B. Cisplatin-gemcitabine

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C. Afatinib

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D. Bevacizumab

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E. Radiotherapy

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Premedications to prevent nausea and vomiting with cisplatin vinorelbine should include:

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A. A neurokinin inhibitor

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B. Metoclopramide

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C. Promethazine

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D. A benzodiazepine

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E. Diphenhydramine

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Which of the following is NOT considered to be an acceptable regimen for advanced stage squamous cell NSCLC?

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A. Carboplatin/paclitaxel

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B. Cisplatin/vinorelbine

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C. Gemcitabine/paclitaxel

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D. Pemetrexed/cisplatin

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E. Gemcitabine/docetaxel

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Which of the following is a reasonable premedication for an EGFR-targeted therapy?

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A. Dexamethasone

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B. Doxycycline

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C. Fosaprepitant

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D. Folate and ...

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