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Chapter 70. Central Nervous System Infections

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A 73-year-old patient with a documented allergy to sulfa agents (bronchoconstriction) should receive which antimicrobial(s) for listeriosis treatment?

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A. Ceftriaxone

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B. Ampicillin

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C. Gentamicin

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D. Vancomycin plus gentamicin

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Which patient would be assumed to be at the highest risk of meningococcal meningitis?

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A. 4-year-old attending daycare

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B. 34-year-old pregnant woman

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C. 78-year-old hospital volunteer

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D. 19-year-old college sophomore

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Which of the following antibiotic therapy should be used for pneumococcal meningitis in a patient with a severe, Type 1 allergy to penicillins and cephalosporins?

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A. Vancomycin

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B. Aztreonam

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C. Meropenem

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D. Sulfamethoxazole-trimethoprim

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Meningococcal vaccine is recommended in which of the following patients:

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A. 2-month-old infant

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B. 67-year-old woman with diabetes

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C. 5-year-old attending daycare

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D. 12-year-old attending public school

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Which of the following antimicrobial agents should be considered in empirical therapy of postneurosurgical meningitis?

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A. Ceftriaxone

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B. Cefepime

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C. Doxycycline

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D. Moxifloxacin

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What is the agent of choice for maintenance therapy in cryptococcal meningitis in a patient with a CD4+ count of 33 cells/mm3 (33 × 106/L)?

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A. Lipid formulation of amphotericin

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B. Posaconazole

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C. Micafungin

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D. Fluconazole

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What is the primary reason for inclusion of vancomycin in empiric treatment of adults with community-acquired bacterial meningitis?

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A. Treatment of methicillin-resistant Staphylococcus aureus (MRSA)

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B. Treatment of drug-resistant Streptococcus pneumoniae

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C. Treatment of drug-resistant Neisseria meningitidis

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D. Treatment of methicillin-resistant Staphylococcus epidermidis (MRSE)

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Which of the following ...

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