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Chapter 69. Antimicrobial Regimen Selection

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Findings consistent with an infection include:

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A. Fever

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B. Elevated WBC count

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C. Elevated procalcitonin

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D. Left shift

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E. All of the above

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_____________ refers to development of resistance occurring in a patient’s nontargeted flora that can cause secondary infections.

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A. Collateral damage

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B. Nonadherence

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C. De-escalation

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D. Pharmacodynamics

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E. Source control

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Which one of the following is true regarding the initial empiric selection of antimicrobial agents?

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A. Empirical selection of antimicrobial therapy should be related to severity of illness.

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B. Given several antimicrobial choices, the antimicrobial most associated with collateral damage is preferred.

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C. In most cases, double coverage is synergistic, prevents the emergence of resistance, improves outcomes, and is superior to monotherapy.

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D. Antimicrobial cost should be the primary factor when deciding on empiric therapy

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E. Consideration of previous antimicrobial exposure is not necessary when choosing empiric therapy.

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All but which one of the following factors is important to consider when selecting an antibiotic dosing regimen?

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A. Source-specific location of infection

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B. Minimum inhibitory concentration (MIC) of the likely pathogens

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C. Route of administration

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D. Antimicrobial agent cost

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E. Metabolism and elimination of the antimicrobial

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Causes of antimicrobial failure include:

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A. Inadequate diagnosis

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B. Development of a new infection with a resistant organism

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C. Poor source control

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D. Nonadherence

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E. All of the above

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Which statement regarding a Gram stain is not correct?

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A. Performed to identify if bacteria are present

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B. If bacteria are present, they will be stained by Gram stain

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C. Gram stain can determine morphological ...

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