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Chapter 44. Thyroid Disorders

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The serum T4 level is not a good test for screening and monitoring for thyroid disease because:

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A. The assay is difficult to perform and not available in most clinical laboratories

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B. The results can be affected by alteration in protein binding, making interpretation difficult

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C. It is too sensitive, with a high percent of false positive results

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D. Serum T3 is a better test since it is the active hormone

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E. All of the above

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The prevalence of hypothyroidism is higher in:

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A. Women

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B. Elderly patients

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C. Patients with other autoimmune endocrine disorders

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D. Patients treated with amiodarone

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E. All of the above are correct

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What is the target TSH range (mIU/L or μIU/mL) for patients being treated for hypothyroidism or hyperthyroidism?

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A. Undetectable

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B. 2.5 to 4.5

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C. 1.4 to 2.5

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D. 0.5 to 4

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E. 4 to 5

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Which of the following is a reasonable choice in treating a patient with newly diagnosed hypothyroidism?

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A. Desiccated thyroid

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B. liotrix

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C. levothyroxine

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D. liothyronine

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E. All are reasonable choices

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Levothyroxine products should not be substituted at refill because:

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A. No marketed products are AB rated by the FDA Orange Book.

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B. All state regulations prohibit the substitution of narrow therapeutic index drugs.

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C. Small differences in bioavailability may result in loss of disease control.

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D. Patients will be nonadherent if it is switched.

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E. A and B are correct.

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Patients with mild or subclinical hypothyroidism should be considered for LT4 therapy if the patient has:

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A. A family history of thyroid disease

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B. Elevated ...

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