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Chapter 37. Schizophrenia

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Which of the following statements is not true?

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A. If the patient has lack of response to two adequate antipsychotic trials, a trial of clozapine should be considered.

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B. All antipsychotics, other than clozapine, have similar efficacy.

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C. It is appropriate to choose an antipsychotic based on which side effects will be most tolerable to the patient.

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D. All antipsychotics have equal risk of weight gain and metabolic disturbances.

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E. The results of the CATIE trial showed some FGAs may be as well tolerated as SGAs.

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Which of the following statements regarding the diagnosis of schizophrenia is true?

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A. The presence of psychosis is diagnostic for schizophrenia.

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B. The presence of disorganization is necessary for diagnosis.

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C. Symptoms must be present for at least 1 week.

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D. Symptoms must be documented by MRI changes.

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E. Social and/or occupational dysfunction must be present.

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Which of the following side effects of antipsychotic medications would have a delayed occurrence of onset that is usually months to years after initiation of the medication?

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A. Sedation

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B. Dry mouth

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C. Tardive dyskinesia

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D. Weight gain

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E. All of the above

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Which of the following schizophrenia symptoms is most likely to respond to antipsychotic treatment?

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A. Hallucinations

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B. Cognition

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C. Impaired judgment

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D. Disorganization

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E. Negative symptoms

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Which of the following situations would be the most appropriate for the use of clozapine?

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A. A 19-year-old patient first presenting with psychotic symptoms

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B. A 65-year-old patient with schizophrenia and multiple myeloma

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C. A 43-year-old patient rehospitalized after nonadherence to olanzapine and risperidone.

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D. A 35-year-old patient rehospitalized after failing treatment with haloperidol

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E. A 33-year-old patient with a lack of response to separate trials of risperidone and aripiprazole

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