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Chapter 30. Multiple Sclerosis

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Which of the following medications is preferred for treatment of acute relapses?

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A. Interferon β-1a

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B. Glatiramer acetate

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C. Methylprednisolone

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D. Tizanidine

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E. Any of the above is acceptable

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Which of the following may help decrease the severity of flu-like symptoms from β-interferons?

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A. Taking ibuprofen about 30 minutes prior to giving the injection

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B. Using the buttocks as an injection site

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C. Applying hydrocortisone 1% cream to the injection site about 30 minutes prior to the injection, then wiping it off with an alcohol wipe just prior to performing the injection

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D. Rotating the injection sites

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E. All of the above

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Which of the following medications may be most helpful for MS-associated fatigue?

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A. Carisoprodol

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B. Tizanidine

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C. Amantadine

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D. Dicyclomine

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E. A and C

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Which of the following toxicities is associated with mitoxantrone therapy?

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A. Neuropathy

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B. Cardiac

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C. Renal

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D. Pulmonary

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E. None of the above

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When should treatment to prevent MS relapses begin?

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A. As soon as possible after diagnosis

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B. After the fourth relapse

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C. When the patient experiences functional impairment

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D. Any time after age 35 years

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E. None of the above

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What is the purpose of symptomatic therapies in MS treatment?

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A. Speed the recovery of the patient after an acute relapse

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B. Decrease the number of relapses

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C. Prevent permanent neurologic damage

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D. Minimize the impact of MS on quality of life

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E. B and D

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