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Chapter 19. Inflammatory Bowel Disease

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Which mesalamine formulation would be most appropriate for a patient with active ulcerative colitis (UC) who has extensive disease?

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A. Intravenous solution

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B. Delayed-release capsule

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C. Enema

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D. Suppository

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Which medication is delivered via intravenous infusion?

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A. Budesonide

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B. Infliximab

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C. Balsalazide

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D. Methotrexate

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Prior to initiating therapy with azathioprine, patients should be evaluated for activity of which enzyme?

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A. Thiopurine methyltransferase

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B. Azathioprine dehydrogenase

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C. Dihydrofolate reductase

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D. Alanine aminotransferase

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Loperamide should be avoided in patients with active UC due to its ability to induce which one of the following complications?

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A. Toxic megacolon

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B. Intestinal stricture

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C. Fistula formation

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D. Pancreatitis

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Probiotics may be most helpful in patients with IBD who have:

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A. Pouchitis

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B. Fistulae

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C. Proctitis

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D. Arthritis

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Which one of the following medications would be contraindicated in a pregnant patient with CD?

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A. Sulfasalazine

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B. Budesonide

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C. Infliximab

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D. Methotrexate

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Which one of the following disorders is a possible extraintestinal manifestation of inflammatory bowel disease?

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A. Erythema nodosum

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B. Migraine headaches

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C. Asthma

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D. Sinusitis

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The mechanism of action of vedolizumab can best be characterized as:

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A. TNF-α inhibition

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B. Purine antagonism

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C. Folate antagonism

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D. Leukocyte adhesion inhibition

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