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Chapter 17. Gastroesophageal Reflux Disease

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Which one of the following GERD symptom is considered complicated and requires further diagnostic evaluation?

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A. Heartburn

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B. Regurgitation

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C. Chronic cough

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D. Difficulty swallowing

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E. Hiatal hernia

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Extraesophageal syndrome associated with GERD refers to:

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A. Erosions of the esophagus

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B. Gastroesophageal reflux symptoms associated with disease processes in organs other than the esophagus

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C. Inflammation of the esophagus

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D. Replacement of the squamous epithelial lining in the esophagus with columnar epithelial lining

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E. Barrett esophagus

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Which of the following PPI regimens is/are preferred as initial treatment in a 60-year-old patient with erosive esophagitis?

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A. Lansoprazole 30 mg once daily × 3 weeks

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B. Pantoprazole 40 mg twice daily × 24 weeks

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C. Esomeprazole 20 mg once daily × 8 weeks

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D. Rabeprazole 20 mg once daily as needed

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E. Any of the above would be a preferred treatment

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Which of the following PPIs would offer dosing flexibility relative to meal timing?

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A. Dexlansoprazole

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B. Lansoprazole

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C. Omeprazole/sodium bicarbonate

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D. Omeprazole

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E. A and C only

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On-demand therapy would be most appropriate in patients with:

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A. Atypical symptoms

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B. Intermittent reflux symptoms

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C. Barrett esophagus

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D. Erosive esophagitis

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E. Strictures

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Which one of the following medications may worsen the symptoms of GERD by decreasing lower esophageal sphincter pressure?

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A. Nifedipine

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B. Alendronate

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C. Naproxen

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D. Quinidine

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E. Ferrous sulfate

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What is the best treatment regimen for a 55-year-old patient who ...

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