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Antimicrobial Regimen Selection

Chapter 69. Antimicrobial Regimen Selection

Findings consistent with an infection include:

A. Fever

B. Elevated WBC count

C. Elevated procalcitonin

D. Left shift

E. All of the above

_____________ refers to development of resistance occurring in a patient’s nontargeted flora that can cause secondary infections.

A. Collateral damage

B. Nonadherence

C. De-escalation

D. Pharmacodynamics

E. Source control

Which one of the following is true regarding the initial empiric selection of antimicrobial agents?

A. Empirical selection of antimicrobial therapy should be related to severity of illness.

B. Given several antimicrobial choices, the antimicrobial most associated with collateral damage is preferred.

C. In most cases, double coverage is synergistic, prevents the emergence of resistance, improves outcomes, and is superior to monotherapy.

D. Antimicrobial cost should be the primary factor when deciding on empiric therapy

E. Consideration of previous antimicrobial exposure is not necessary when choosing empiric therapy.

All but which one of the following factors is important to consider when selecting an antibiotic dosing regimen?

A. Source-specific location of infection

B. Minimum inhibitory concentration (MIC) of the likely pathogens

C. Route of administration

D. Antimicrobial agent cost

E. Metabolism and elimination of the antimicrobial

Causes of antimicrobial failure include:

A. Inadequate diagnosis

B. Development of a new infection with a resistant organism

C. Poor source control

D. Nonadherence

E. All of the above

Which statement regarding a Gram stain is not correct?

A. Performed to identify if bacteria are present

B. If bacteria are present, they will be stained by Gram stain


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