Allergic and Pseudoallergic Drug Reactions
Chapter 54. Allergic and Pseudoallergic Drug Reactions
Of all adverse drug reactions reported in hospitals, the percentage of these that are allergic or immunologic is:
Fifteen minutes after the start of a piperacillin/tazobactam infusion, the patient develops severe itching and difficulty breathing. What type of Gell and Coombs reaction is occurring?
A site of drug metabolism that might explain why skin reactions occur with a variety of different drugs is:
What type(s) of Gell and Coombs reactions can penicillins cause?
E. Types I, II, III, and IV
Pseudoallergic drug reactions differ from allergic reactions in that they:
A. Are based on the structure of the drug
B. Involve the activation of the patient’s immune system
C. Represent common biological functions such as direct histamine release
D. Require the drug to be bound to a protein
E. Involve T-cell activation
Of patients claiming to have penicillin allergies, what percentage will have a negative penicillin skin test?